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Studies designed to provide insight into clinical practice in the real world are referred to as pragmatic trials. They are often described as focusing on practical aspects of design which include the recruitment process and consent, adhering and the use of standard equipment.
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A practical trial that employs different investigators and participants from various geographical regions is the Home Blood Pressure Management study (HBPM). This type of heterogeneity is essential for pragmatic trials to be able to prove their validity and also reduces the chance of bias in the results. Too much heterogeneity, however can result in problems with the trial design.
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The goal of pragmatic trials is to mimic real-life situations and achieve maximum validity externally. They are typically commissioned by policymakers and practitioners to help guide their decisions. They can also be a great method of determining the causal relationship between an intervention and its results. They should, however, not, be used to replace explanatory studies.
프라그마틱 데모 is controversial and there are questions about whether pragmatic trials should replace explanatory trials or complement them. Schwartz and Lellouch1 suggested the distinction between explanation trials, which confirm the clinical or physiological hypothesis, and pragmatic trials, which inform the policy and practice of. They also suggested a framework dubbed PRECIS for pragmatic trials.2 The tool was designed to define the traits of a pragmatic research study which includes the recruitment, design, and delivery of the intervention, and follow-up.
There is a positive increase in the number pragmatic trials published. A recent Medline search using the keywords naturalistic and pragmatic, which was limited to controlled trials randomized to control (RCTs) produced 34 articles, shown in red in Figure 2. This is an indication that the health science community is becoming increasingly sensitized to the subject of pragmatic thinking. It is important to keep in mind that the majority of these studies were conducted in primary care settings.